Background:
@EN Morphologic characteristics of the human embryonic and fetal periderm according to body region are not very clearly defined.
@ES Objective:
@EN We have tried to clarify the sequential development of periderm regionally.
@ES Method:
@EN Skin samples were obtained from 12 human embryos and fetuses ranging from 4 to 23 estimated gestational ages(EGA) and divided regionally into scalp, face, back, abdomen, thigh and sole. Specimens were observed by scanning with an electron
microscope.
@ES Results:
@EN Human embryonic and fetal periderm show distinct morphologic changes as follows along its own sequence of development : flattened surface, elevated surface, formation of incomplete bleb. single bleb stage, multiple-complex bleb stage,
formation
of
regressing bleb. Then towards the and of the second trimester, most of theperidermal cells are completely regressed. Regional variation in peridermal development is not evident during the embryonic period, but earlier development is apparent in
the
sole, face and scalp especially in sole compared to other areas during the late first ad second trmester after EGA 9 wks.
@ES Conclusion:
@EN The periderm, which can be seen only in embryonic and fetal epidermis, shows distinct sequential developmental changes with regional variation. ( Kor J Dermatol 1994 ; 32(3) : 427~437)
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